Research & Evidence
Floater-focused research. Broader daily eye nutrition.
Explore research on eye floaters, retinal carotenoids, macular pigment, and tear-film measures related to dry eye and screen use. See the evidenceOur approach
Built around floater research.
Broadened for daily eye nutrition.
Haro Clear combines five nutrient categories represented in
FLIES
Floater Intervention Study (FLIES): a 2021 trial of a five-nutrient supplement for adults with symptomatic vitreous floaters.
, 900 mg of fruit enzymes per daily serving, and the retinal carotenoids lutein and zeaxanthin.
Retinal carotenoids
8mglutein + zeaxanthin
Carotenoids found in the retina and lens, included in every daily Haro Clear serving.
Daily enzyme serving
900mgbromelain + papain
The largest ingredients in the formula by weight.
FLIES Floater Intervention Study (FLIES): a 2021 trial of a five-nutrient supplement for adults with symptomatic vitreous floaters. connection
Five targeted micronutrients.
Broader eye nutrition
9complementary ingredients
Enzymes, carotenoids and targeted micronutrients in one routine.Fruit enzyme study A 2022 trial of bromelain, papain and ficin in adults with vitreous floaters. : what it tested
Two daily capsules of Haro Clear provide 600 mg bromelain and 300 mg papain. Together, these fruit-derived enzymes contribute 900 mg and are the formula’s largest ingredients by weight.
Published visual evidence
Compare the study’s before-and-after figures.
Case examples reproduced from the published 2022 mixed-fruit-enzyme study.
Before: A 55-year-old woman had one eye floater visible on a B-scan at the start of the study.
After three months: The paper reports that the floater was significantly reduced on the follow-up B-scan after she received the mixed fruit enzyme supplement tested in the study.
Before: A 58-year-old man with diabetes had a dark-red cloud over the retina caused by bleeding inside the eye.
After three months: The paper reports that the clouding decreased and his vision improved from 20/200 to 20/40 after he received the mixed fruit enzyme supplement tested in the study.
What was tested?
The 2022 study included 160 participants with spontaneous vitreous opacities and 64 with hemorrhage-related opacities. These are different clinical situations; the before-and-after examples should be read in that context. Over three months, participants received a vitamin C comparator or one, two or three daily capsules of a combination containing bromelain, papain and ficin. The researchers reported improvements with the combination tested.
How to read the findings
Haro Clear centers its fruit-enzyme component on 600 mg bromelain and 300 mg papain, paired with targeted micronutrients, lutein and zeaxanthin in a nine-ingredient formula.
This trial tested bromelain, papain and ficin together. Haro Clear does not contain ficin and was not tested in this trial; these findings do not establish equivalent results for Haro Clear.
- Read the complete study Ma et al. (2022) · Journal of Clinical Medicine · 11(22):6710 · DOI: 10.3390/jcm11226710
About our processResearch transparency
We cite the sources behind our study explanations and identify the tested ingredients, doses, populations and findings. Results apply to the formulas and people studied; they do not establish equivalent results for Haro Clear.
Disclosure: Haro Health owns and sells Haro Clear.
We review affected content when the label, source information or evidence changes. To flag an error, email hello@harohealth.com with the page link and the wording you want us to check. Please do not send private medical records.
Review status: Updated study explanations are under review. Previously recorded review: September 13, 2026.